Seeing as this question has been going on for the last few days, we've decided we might as well try and answer it. First let's take a look back at The Play.
And now the Mississippi Miracle.
Now let's get to which one is better.
1. Number of laterals - The Play has 5. Mississippi Miracle has 15. Edge Mississippi Miracle.
2. Play Calls - Both announcers have their heads explode. Even.
3. Finish - The Play has the Stanford Band on the field during the final seconds. Mississippi Miracle has Trinity run out onto the field after the final TD. Edge The Play.
4. Number of band members injured - The Play has 1. Mississippi Miracle has zero. Huge edge to The Play.
5. Number of controversial non-calls - The Play has 2, one player is pretty clearly down, and one lateral was potentially a forward pass. Mississippi Miracle has at least one potential holding penalty not called. Edge The Play.
6. Classic postgame quotes - The Play had John Elway saying "This was an insult to college football... They [the officials] ruined my last game as a college football player." Mississippi Miracle had Millsaps coach Mike DuBose saying "The worst part about it is we had five or six guys just quit on the play." Edge clearly to The Play.
7. Impact of loss - The Play prevented Elway from ever playing in a bowl game while at Stanford. Mississippi Miracle prevented Millsaps from clinching a D-III playoff berth for a week. Massive edge to The Play.
So there you have it. Because of the magnitude of The Play's impact on royally screwing over John Elway's college career, combined with the fact that a band member was massacred in the process, clearly gives The Play the definitive title of best play in college football history over the Mississippi Miracle.